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List of results
- CNV WG + (carry out mega-analysis or meta-analysis on existing structural MRI and DTI data coupled with CNVs.)
- 22q WG + (carry out meta-analysis of existing structural MRI and DTI data of children and adults with the 22q11.2 deletion and healthy controls.)
- Relatives WG + (collect MRI scans of first-degree relatives of patients with severe mental illness and compare those with controls (and their probands))
- Proj ENIGMA3 Cortical GWAS + (GWAS)
- Proj Deficit SCZ + (reports effect sizes for subcoritical volume and hippocampus)
- StorageDisease WG + (define relations between genetics brain morphometry cognitive status and clinical signs in lysosomal storage diseases)
- ORIGINs WG + (determine how genetic and environmental factors influence the development of brain morphometry anatomical and functional connectivity and cognitive and emotional function from birth to age 6.)
- BD WG + (determine the best endophenotypes for distinguishing cases from controls.)
- Proj Early Onset Psychosis SCZ BD + (reports effect sizes for subcortical and hipppocampal volume abnormalities in early onset psychosis)
- Proj GRS SCZ + (examines association between genetic risk scores for multiple disorders (e.g. SZ BD MDD and brain imaging data). First protocol will require GWAS and structural imaging data.)
- Proj Cross Disorder SCZ BD MDD + (examines differences in subcortical volumes hippocampal volumes cortical thickness and surface area between schizophrenia mdd and bp and performs an initial supervised classification analysis)
- Proj Hippocampal Subregion SCZ + (examines effect sizes of hippocampal subfield volumes using FreeSurfer 6.0 (or 6.0dev))
- Proj Childhood Trauma SCZ + (examines effects of childhood trauma as well as possible interaction with sex on cortical thickness and surface area and symptom profile)
- Proj Laterality Cortical + (examines laterality of cortical thickness and surface area in healhty volunteers)
- Proj Laterality Subcortical + (examines laterality of subcortical and hippocampal volumes in healthy volunteers)
- Proj Aggression SCZ + (examines relationship between brain structure and agression with an interest in conducting a future GWAS (perhaps bivariate GWAS?))
- Proj Negative Symptoms SCZ + (examines relationship between left orbitofrontal thickness and negative symptoms)
- Proj Positive Symptoms SCZ + (examines relationship between superior temporal gyrus thickness and positive symptoms)
- Proj Cannabis SCZ + (examines the effect of cannabis use on structural abnormalities in schizophrenia)
- HippoSub WG + (examining the test-retest and trans-platform reliability of the most recent FREESURFER algorithm (version 6.0) with an aim to circulate standardized subregion segmentation protocols based on this algorithm in the coming months.)
- Transgender WG + (explore by virtue of imaging-based mega-analysis the underlying neurobiology of transgenderism.)
- Sleep WG + (explore meta-analyses of a wide range of neuroimaging modalities in physiology of sleep and its disorders)
- Schizophrenia WG + (explore meta-analyses of cortical and subcortical structures across many different studies and datasets)
- Plasticity WG + (focusses on individual differences in longitudinal brain changes.)
- Proj GWAS DTI + (gwas of regional dti measures)
- Proj Schizotypy + (http://enigma.ini.usc.edu/ongoing/enigma-schizotypy/)
- Tourettes WG + (identify brain regions and brain circuits that are involved in the neurobiology of TS and investigate how these relate to genomic background.)
- Laterality WG + (identify common genetic variants that influence left-right asymmetrical aspects of brain structure and function)
- MDD WG + (identify imaging markers that robustly discriminate MDD patients from healthy controls across many different samples using carefully a priori planned standardized image processing and statistical analysis protocols.)
- EOP WG + (identify markers that robustly discriminat … identify markers that robustly discriminate adolescents with EOP from healthy controls differentiate among the different EOP syndromes (including early-onset schizophrenia (EOS) and early-onset bipolar (EOBP) spectrum disorders) by studying the genetic and brain neuroanatomical and functional characteristics across ages and different studies and datasets.s ages and different studies and datasets.)
- STB WG + (identify neurobiological variations associated with suicidal ideations and behaviors to ultimately leverage information from brain structure function along with clinical and demographic factors to predict the likelihood of a future suicidal attempt.)
- Anxiety WG + (improve our understand of anxiety disorders via large-scale collaborative neuroimaging)
- Irritability WG + (improving our understanding of how a broadly based psychiatric symptom irritability may relate to brain and genomic changes.)
- Stroke WG + (improving our understanding of how changes in post-stroke neuroanatomy may relate to motor recovery after stroke.)
- Epilepsy WG + (improving our understanding of in vivo neuroanatomical disruptions in people with epilepsy compared to healthy individuals in the general population.)
- EatingDisorders WG + (improving our understanding of structural brain changes in patients with anorexia nervosa and Bulimia nervosa and how those changes normalize during or after recovery)
- CancerChemo WG + (investigate the impacts of cancer and chemotherapy on the brain.)
- EEG WG + (performing a meta-analysis of functional brain activity as measured by scalp recorded electrical brain activity also known as Electroencephalography)
- Shape WG + (provides a streamlined tool to perform fine-grained analysis of deep gray matter morphometry using standard brain MRI)
- Proj Deficit SCZ + (reports effect sizes for subcoritical volume and hippocampus)
- Proj Cerebellum SCZ + (reports effect sizes for structural cerebellar abnormalities in schizophrenia)
- Proj Relatives SCZ BD + (reports effect sizes for subcortical and global brain measures in schizophrenia and bipolar disorder relatives)
- Proj Subcortical Shapes SCZ + (reports effect sizes for subcortical and hippocampal shape)
- Proj Subcortical SCZ + (reports effect sizes for subcortical and hippocampal volume abnormalities in schizophrenia)
- Proj Early Onset Psychosis SCZ BD + (reports effect sizes for subcortical and hipppocampal volume abnormalities in early onset psychosis)
- Proj Longitudinal SCZ + (reports effect sizes for subcortical and hipppocampal volume abnormalities in first-episode schizophrenia)
- Proj Sulci SCZ + (reports effect sizes for sulcal abnormalties in schizophrenia)
- Proj Cortical SCZ + (reports effects sizes for cortical thickness and surface area abnormalities in schizophrenia)
- Proj DTI SCZ + (reports effects sizes for regional DTI measures)
- Proj Normal Variation Cortical + (reports on normal variation for cortical thickness and surface area by age and gender in healthy volunteers)
- Proj Normal Variation Subcortical + (reports on normal variation for subcortial and hippocampal volumes by age and gender in healthy volunteers)